RGS6 antibody (AA 7-357)

Catalog No. ABIN7876488

The Rabbit Polyclonal anti-RGS6 antibody is suitable to detect RGS6 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, FACS and IHC (p).

Quick Overview for RGS6 antibody (AA 7-357) (ABIN7876488)

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RGS6 Antibody

Binding Specificity: AA 7-357

Purpose: RGS6 Antibody

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids D7-E357) was used as the immunogen for the RGS6 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RGS6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RGS6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RGS6

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Alternative Name: RGS6

Background: Regulator of G-protein signaling 6 is a protein that in humans is encoded by the RGS6 gene. This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.

UniProt: P49758

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling