Occludin antibody (AA 7-367)

Catalog No. ABIN7876490

This Rabbit Polyclonal antibody specifically detects Occludin in WB and ELISA. It exhibits reactivity toward Mouse and Rat.

Quick Overview for Occludin antibody (AA 7-367) (ABIN7876490)

Target: Occludin (OCLN)

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Occludin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Occludin Antibody

Binding Specificity: AA 7-367

Purpose: Ocln Antibody / Occludin

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant mouse protein (amino acids E7-Y367) was used as the immunogen for the Ocln antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Ocln antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Ocln antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Occludin

Target: Occludin (OCLN)

Alternative Name: Ocln

Background: Occludin is an enzyme (EC 1.6) that oxidizes NADH. Predicted to enable protein domain specific binding activity. Involved in negative regulation of gene expression and tight junction organization. Located in several cellular components, including apical plasma membrane, apicolateral plasma membrane, and bicellular tight junction. Is expressed in several structures, including alimentary system, brain, genitourinary system, respiratory system, and sensory organ. Human ortholog(s) of this gene implicated in Crohn's disease and pseudo-TORCH syndrome 1. Orthologous to human OCLN (occludin).

UniProt: Q61146

Pathways: Cell-Cell Junction Organization, Hepatitis C