TRIM24 antibody (AA 706-964)

Catalog No. ABIN7876594

The Mouse Monoclonal anti-TRIM24 antibody (Clone 4G6C2) (ABIN7876594) specifically detects TRIM24 in WB, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TRIM24 antibody (AA 706-964) (ABIN7876594)

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRIM24 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4G6C2

Product Details anti-TRIM24 Antibody

Binding Specificity: AA 706-964

Purpose: TRIM24 Antibody / TIF1 alpha / TIF1A

Purification: Antigen affinity purified

Immunogen: Recombinant human TRIM24 protein (amino acids A706-D964) was used as the immunogen for the TRIM24 antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the TRIM24 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TRIM24 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Alternative Name: TRIM24

Background: Tripartite motif-containing 24 (TRIM24) also known as transcriptional intermediary factor 1a (TIF1a) is a protein that, in humans, is encoded by the TRIM24 gene. The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: O15164