Recombinant CD207 antibody (AA 74-213)

Catalog No. ABIN7876704

The Mouse Monoclonal anti-CD207 antibody is suitable to detect CD207 in samples from Human. It has been validated for ELISA.

Quick Overview for Recombinant CD207 antibody (AA 74-213) (ABIN7876704)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD207 antibody is un-conjugated

Application: ELISA

Grade: Carrier-free

Clone: RLGRN-1821

Product Details anti-CD207 Antibody

Binding Specificity: AA 74-213

Purpose: Recombinant Langerin Antibody / CD207 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 74-213 was used as the immunogen for the recombinant Langerin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Langerin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant Langerin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Alternative Name: Langerin

Background: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

UniProt: Q9UJ71