GLUL antibody (AA 74-373)

Catalog No. ABIN7876717

The Rabbit Polyclonal anti-GLUL antibody (ABIN7876717) specifically detects GLUL in WB, ELISA, IF, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GLUL antibody (AA 74-373) (ABIN7876717)

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLUL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-GLUL Antibody

Binding Specificity: AA 74-373

Purpose: GLUL Antibody / Glutamine Synthetase

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids N74-N373) was used as the immunogen for the GLUL antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the GLUL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the GLUL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for GLUL

Target: GLUL (Glutamate-Ammonia Ligase (GLUL))

Alternative Name: GLUL

Background: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants.

UniProt: P15104

Pathways: Positive Regulation of Peptide Hormone Secretion