EED antibody (AA 77-441)

Catalog No. ABIN7876765

The Rabbit Polyclonal anti-EED antibody (ABIN7876765) specifically detects EED in WB, ELISA and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for EED antibody (AA 77-441) (ABIN7876765)

Target: EED (Embryonic Ectoderm Development (EED))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EED antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-EED Antibody

Binding Specificity: AA 77-441

Purpose: Embryonic ectoderm development protein Antibody / EED

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K77-R441) was used as the immunogen for the Embryonic ectoderm development protein antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Embryonic ectoderm development protein antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Embryonic ectoderm development protein antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for EED

Target: EED (Embryonic Ectoderm Development (EED))

Alternative Name: Embryonic ectoderm development protein

Background: Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta-7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. Furthermore, this protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

UniProt: O75530