HERC5 antibody (AA 793-1024)

Catalog No. ABIN7876807

The Rabbit Polyclonal anti-HERC5 antibody (ABIN7876807) specifically detects HERC5 in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for HERC5 antibody (AA 793-1024) (ABIN7876807)

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-HERC5 Antibody

Binding Specificity: AA 793-1024

Purpose: HERC5 Antibody

Purification: Affinity purified

Immunogen: Amino acids F793-G1024 from the human protein were used as the immunogen for the HERC5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HERC5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HERC5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HERC5

Target: HERC5 (Hect Domain and RLD 5 (HERC5))

Alternative Name: HERC5

Background: Probable E3 ubiquitin-protein ligase HERC5 is an enzyme that in humans is encoded by the HERC5 gene. It is mapped to 4q22.1. This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets.

UniProt: Q9UII4