SNX15 antibody (AA 8-327)

Catalog No. ABIN7876821

The Rabbit Polyclonal anti-SNX15 antibody is suitable to detect SNX15 in samples from Human. It has been validated for ELISA and WB.

Quick Overview for SNX15 antibody (AA 8-327) (ABIN7876821)

Target: SNX15 (Sorting Nexin 15 (SNX15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX15 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SNX15 Antibody

Binding Specificity: AA 8-327

Purpose: Sorting nexin 15 Antibody / SNX15

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids D8-K327) was used as the immunogen for the Sorting nexin 15 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Sorting nexin 15 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Sorting nexin 15 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Alternative Name: Sorting nexin 15

Background: Sorting nexin-15 is a protein that in humans is encoded by the SNX15 gene. This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

UniProt: Q9NRS6