Recombinant CA9 antibody (Extracellular, N-Term)

Catalog No. ABIN7876852

The Mouse Monoclonal anti-CA9 antibody (Clone rCA9-9937) (ABIN7876852) specifically detects CA9 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant CA9 antibody (Extracellular, N-Term) (ABIN7876852)

Target: CA9 (Carbonic Anhydrase IX (CA9))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CA9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RCA9-9937

Product Details anti-CA9 Antibody

Binding Specificity: AA 80-100, Extracellular, N-Term

Purpose: Recombinant CA9 Antibody / Carbonic anhydrase 9

Purification: Protein G affinity

Immunogen: The extracellular N-terminal proteoglycan-like region of the human protein was used as the immunogen for the recombinant CA9 antibody. The epitope is localized to the amino acids 80-100 region.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the recombinant CA9 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant CA9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CA9

Target: CA9 (Carbonic Anhydrase IX (CA9))

Alternative Name: CA9

Background: Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200).In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.

UniProt: Q16790