Elastase 3B antibody (AA 82-238)

Catalog No. ABIN7876916

This Mouse Monoclonal antibody specifically detects Elastase 3B in ELISA. It exhibits reactivity toward Human.

Quick Overview for Elastase 3B antibody (AA 82-238) (ABIN7876916)

Target: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Elastase 3B antibody is un-conjugated

Application: ELISA

Clone: CELA3B-1758

Product Details anti-Elastase 3B Antibody

Binding Specificity: AA 82-238

Purpose: CELA3B Antibody / Elastase 3B

Purification: Protein A/G affinity

Immunogen: A portion of amino acids 82-238 was used as the immunogen for the CELA3B antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CELA3B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CELA3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Elastase 3B

Target: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Alternative Name: CELA3B

Background: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function.

UniProt: P08861