GLA antibody (AA 83-112)

Catalog No. ABIN7876930

The Rabbit Polyclonal anti-GLA antibody (ABIN7876930) specifically detects GLA in WB, FACS, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for GLA antibody (AA 83-112) (ABIN7876930)

Target: GLA (Galactosidase, alpha (GLA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GLA Antibody

Binding Specificity: AA 83-112

Purpose: Galactosidase alpha Antibody / Gla

Purification: Purified

Immunogen: A portion of amino acids 83-112 from the human protein was used as the immunogen for the Galactosidase alpha antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Galactosidase alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Galactosidase alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GLA

Target: GLA (Galactosidase, alpha (GLA))

Alternative Name: Galactosidase alpha

Background: GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interactome