The Mouse Monoclonal anti-ZNF239 antibody (Clone PCRP-ZNF239-2A10) (ABIN7876936) specifically detects ZNF239 in FACS.
The antibody is reactive with Human samples.
ZNF239
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the ZNF239 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
-20 °C
Storage Comment
Aliquot the ZNF239 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
ZNF239
(Zinc Finger Protein 239 (ZNF239))
Alternative Name
ZNF239
Background
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.