NUB1 antibody (AA 87-117)

Catalog No. ABIN7877012

This Rabbit Polyclonal antibody specifically detects NUB1 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for NUB1 antibody (AA 87-117) (ABIN7877012)

Target: NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NUB1 Antibody

Binding Specificity: AA 87-117

Purpose: NUB1 Antibody / NEDD8 ultimate buster 1 / NYREN18

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 87-117 from the human protein was used as the immunogen for the NYREN18 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the NYREN18 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NYREN18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NUB1

Target: NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

Alternative Name: NUB1

Background: NUB1/NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.

UniProt: Q9Y5A7