ERLIN2 antibody (AA 87-339)

Catalog No. ABIN7877018

This Rabbit Polyclonal antibody specifically detects ERLIN2 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ERLIN2 antibody (AA 87-339) (ABIN7877018)

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-ERLIN2 Antibody

Binding Specificity: AA 87-339

Purpose: Erlin-2 Antibody

Purification: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids D87-N339) was used as the immunogen for the Erlin-2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Erlin-2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Erlin-2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ERLIN2

Target: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Alternative Name: Erlin-2

Background: Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene. This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: O94905