MTR antibody (AA 880-1095)

Catalog No. ABIN7877036

This Rabbit Polyclonal antibody specifically detects MTR in WB, ELISA, IHC (p) and FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for MTR antibody (AA 880-1095) (ABIN7877036)

Target: MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase (MTR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTR antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-MTR Antibody

Binding Specificity: AA 880-1095

Purpose: MTR Antibody / Methionine synthase

Purification: Affinity purified

Immunogen: A human recombinant protein (amino acids V880-D1095) was used as the immunogen for the MTR antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MTR antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the MTR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MTR

Target: MTR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase (MTR))

Alternative Name: MTR

Background: Methionine synthase, also known as MS, MeSe, and MetH, is responsible for the regeneration of methionine from homocysteine. In humans it is encoded by the MTR gene (5-methyltetrahydrofolate-homocysteine methyltransferase). It is mapped to 1q43. This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

UniProt: Q99707

Pathways: Methionine Biosynthetic Process