Aurora Kinase B antibody (AA 89-251)

Catalog No. ABIN7877053

The Mouse Monoclonal anti-Aurora Kinase B antibody (Clone ARRK2-1) (ABIN7877053) specifically detects Aurora Kinase B in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Aurora Kinase B antibody (AA 89-251) (ABIN7877053)

Target: Aurora Kinase B (AURKB)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aurora Kinase B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: ARRK2-1

Product Details anti-Aurora Kinase B Antibody

Binding Specificity: AA 89-251

Purpose: AURKB Antibody / Aurora B (azide and preservative free)

Purification: Protein G affinity

Immunogen: Amino acids 89-251 were used as the immunogen for this AURKB antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the AURKB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the AURKB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Alternative Name: AURKB

Background: Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]

UniProt: Q96GD4

Pathways: TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades