Recombinant TRPS1 antibody (AA 900-1100)

Catalog No. ABIN7877124

The Rabbit Monoclonal anti-TRPS1 antibody is suitable to detect TRPS1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant TRPS1 antibody (AA 900-1100) (ABIN7877124)

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TRPS1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TRPS1-8008R

Product Details anti-TRPS1 Antibody

Binding Specificity: AA 900-1100

Purpose: TRPS1 Antibody / Tricho-rhino-phalangeal syndrome type I

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 900-1100) from the human protein was used as the immunogen for the TRPS1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the TRPS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TRPS1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Alternative Name: TRPS1

Background: Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells.

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus