FGF21 antibody (AA 91-209)

Catalog No. ABIN7877138

This Mouse Monoclonal antibody specifically detects FGF21 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for FGF21 antibody (AA 91-209) (ABIN7877138)

Target: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF21 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FGF21-3691

Product Details anti-FGF21 Antibody

Binding Specificity: AA 91-209

Purpose: FGF21 Antibody / Fibroblast Growth Factor 21

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 91-209 from the human protein was used as the immunogen for the FGF21 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the FGF21 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the FGF21 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for FGF21

Target: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Alternative Name: FGF21

Background: Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10-FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

UniProt: Q9NSA1

Pathways: RTK Signaling