WAPAL antibody (AA 916-1190)

Catalog No. ABIN7877150

This Rabbit Polyclonal antibody specifically detects WAPAL in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for WAPAL antibody (AA 916-1190) (ABIN7877150)

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WAPAL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-WAPAL Antibody

Binding Specificity: AA 916-1190

Purpose: WAPL Antibody / FOE / Wings apart-like protein homolog

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids Q916-C1190) was used as the immunogen for the WAPL antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the WAPL antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the WAPL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for WAPAL

Target: WAPAL (Wings Apart-Like Protein Homolog (WAPAL))

Alternative Name: WAPL

Background: WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth. It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1). WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by directly interacting with its regulatory subunits. WAPL is a new regulator of the development and metastasis of cancerous tissue.

UniProt: Q7Z5K2

Pathways: Chromatin Binding