PFN2 antibody (AA 96-138)

Catalog No. ABIN7877242

The Rabbit Polyclonal anti-PFN2 antibody (ABIN7877242) specifically detects PFN2 in WB, ELISA, IHC (p) and FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PFN2 antibody (AA 96-138) (ABIN7877242)

Target: PFN2 (Profilin 2 (PFN2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-PFN2 Antibody

Binding Specificity: AA 96-138

Purpose: PFN2 Antibody / Profilin 2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E96-S138) was used as the immunogen for the PFN2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PFN2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PFN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PFN2

Target: PFN2 (Profilin 2 (PFN2))

Alternative Name: PFN2

Background: Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

UniProt: P35080

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis