NECAB3 antibody (AA 97-339)

Catalog No. ABIN7877271

The Rabbit Polyclonal anti-NECAB3 antibody is suitable to detect NECAB3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for NECAB3 antibody (AA 97-339) (ABIN7877271)

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NECAB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-NECAB3 Antibody

Binding Specificity: AA 97-339

Purpose: NECAB3 Antibody / N-terminal EF-hand calcium-binding protein 3

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids D97-D339) was used as the immunogen for the NECAB3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NECAB3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NECAB3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NECAB3

Target: NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Alternative Name: NECAB3

Background: N-terminal EF-hand calcium-binding protein 3 is a protein that in humans is encoded by the NECAB3 gene. The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q96P71