The Rabbit Polyclonal anti-Surfactant Protein C antibody is suitable to detect Surfactant Protein C in samples from Mouse and Rat. It has been validated for WB and ELISA.
SFTPC
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
5E6A9
unconjugated
Application Notes
Optimal dilution of the Sftpc antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
4 °C,-20 °C
Storage Comment
After reconstitution, the Sftpc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
Surfactant Protein C (SFTPC)
Alternative Name
Sftpc
Background
SFTPC (Surfactant pulmonary -associated protein C), also known as SFTP2, SPC, PSP-C or PULMONARY SURFACTANT PROTEIN SP5, is a protein that in humans is encoded by the SFTPC gene. It is a membrane protein which manufactures surfactant. Glasser et al.(1988) assigned the SFTPC gene, symbolized SFTP2 by the Human Gene Mapping nomenclature committee, to chromosome 8 by hybridization to somatic cell hybrid DNA. Wood et al.(1994) identified 4 cosmids at the SFTP2 locus by cDNA hybridization. Using a polymorphic CA repeat in the SFTP2 gene and linkage analysis in 8 CEPH families, they located the gene close to D8S298, maximum lod = 19.3 at theta = 0.01. They regionalized the gene to 8p21 by fluorescence in situ hybridization. Moore et al.(1992) showed that the corresponding mouse gene, Sftp2, maps to chromosome 14.