Recombinant Annexin a1 antibody (full length)

Catalog No. ABIN7877679

The Mouse Monoclonal anti-Annexin a1 antibody is suitable to detect Annexin a1 in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for Recombinant Annexin a1 antibody (full length) (ABIN7877679)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RANXA1-9145

Product Details anti-Annexin a1 Antibody

Binding Specificity: full length

Purpose: ANXA1 Antibody / Annexin A1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human Annexin A1 protein was used as the immunogen for the ANXA1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the ANXA1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the ANXA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: ANXA1

Background: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

UniProt: P04083

Pathways: Hormone Transport