CSNK1A1 antibody (full length)

Catalog No. ABIN7877825

This Mouse Monoclonal antibody specifically detects CSNK1A1 in IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for CSNK1A1 antibody (full length) (ABIN7877825)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSNK1A1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: KRT1-1840

Product Details anti-CSNK1A1 Antibody

Binding Specificity: full length

Purpose: CK1 Antibody / Cytokeratin 1 / Keratin 1

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human Cytokeratin 1 protein was used as the immunogen for this CK1 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the CK1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CK1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: CK1

Background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.

UniProt: P04264

Pathways: WNT Signaling, Hedgehog Signaling