Recombinant CD151 antibody (full length)

Catalog No. ABIN7877842

The Rabbit Monoclonal anti-CD151 antibody (Clone CD151-9297R) (ABIN7877842) specifically detects CD151 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant CD151 antibody (full length) (ABIN7877842)

Target: CD151

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD151 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CD151-9297R

Product Details anti-CD151 Antibody

Binding Specificity: full length

Purpose: Recombinant CD151 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human CD151 protein was used as the immunogen for the recombinant CD151 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant CD151 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant CD151 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD151

Target: CD151

Alternative Name: CD151

Background: CD151 is involved in a wide variety of cell biological processes, including cell adhesion and the transport of integrins via vesicles. The human CD151 gene maps to chromosome 11p15.5 and encodes a 253 amino acid protein, which belongs to the tetraspan (4TM) superfamily. CD151 can associate with several integrin chains including beta1, beta3, beta4, alpha2, alpha3, alpha5 and alpha6 integrins. CD151 may provide a framework for the spatial organization of both type I and type II hemidesmosomes, which are specialized junctional complexes that function as cell attachment sites for binding to basement membranes. CD151 RNA transcript (1.6 kb) can be detected in MO7e cells, bone marrow stromal cells, C11 endothelial cells, HUVEC and several myeloid leukemia cell lines, however, no transcript is detected in brain and the lymphoblastoid cell lines MOLT-4 and BALM-1. Leu 149-Glu 213 of CD151 is the interface through which Integrin alpha3/beta1 can bind. CD151 can enhance cell motility, invasion and metastasis of cancer cells in a focal adhesion kinase dependent manner.

UniProt: P48509