Recombinant CD99 antibody (full length)

Catalog No. ABIN7877973

The Mouse Monoclonal anti-CD99 antibody is suitable to detect CD99 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CD99 antibody (full length) (ABIN7877973)

Target: CD99

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD99 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RMIC2-3317

Product Details anti-CD99 Antibody

Binding Specificity: full length

Purpose: CD99 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human MIC2/CD99 protein was used as the immunogen for the CD99 antibody.

Isotype: IgM, kappa

Application Details

Application Notes: Optimal dilution of the CD99 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD99 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD99

Target: CD99

Alternative Name: CD99

Background: Recognizes a sialoglycoprotein of 27-32 kDa, identified as CD99, or MIC2 gene product, or E2 antigen. MIC2 gene is located in the pseudo-autosomal region of the human X and Y chromosome. MIC2 gene encodes two distinct proteins, which are produced by alternative splicing of the CD99 gene transcript and are identified as bands of 30 and 32 kDa (p30/32).Although its function is not fully understood, CD99 is implicated in various cellular processes including homotypic aggregation of T cells, upregulation of T cell receptor and MHS molecules, apoptosis of immature thymocytes and leukocyte diapedesis.CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes, and granulosa cells of the ovary. Most pancreatic islet cells, Sertoli cells of the testis, and some endothelial cells express this antigen. Mature granulocytes express very little or no CD99. MIC2 is strongly expressed on Ewing s sarcoma cells and primitive peripheral neuroectodermal tumors.

UniProt: P14209