CKM antibody (full length)

Catalog No. ABIN7878037

The Mouse Monoclonal anti-CKM antibody (Clone CKMM-3341) (ABIN7878037) specifically detects CKM in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for CKM antibody (full length) (ABIN7878037)

Target: CKM (Creatine Kinase, Muscle (CKM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CKM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CKMM-3341

Product Details anti-CKM Antibody

Binding Specificity: full length

Purpose: Creatine Kinase M Antibody / CKM (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length CKM protein was used as the immunogen for the Creatine Kinase M antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the Creatine Kinase M antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Creatine Kinase M antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CKM

Target: CKM (Creatine Kinase, Muscle (CKM))

Alternative Name: Creatine Kinase M

Background: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.

UniProt: P06732