Cyclin A1 antibody (full length)

Catalog No. ABIN7878057

The Mouse Monoclonal anti-Cyclin A1 antibody is suitable to detect Cyclin A1 in samples from Human and Xenopus laevis. It has been validated for WB.

Quick Overview for Cyclin A1 antibody (full length) (ABIN7878057)

Target: Cyclin A1 (CCNA1)

Reactivity: Human, Xenopus laevis

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin A1 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: Carrier-free

Clone: XLA1-3

Product Details anti-Cyclin A1 Antibody

Binding Specificity: full length

Purpose: Cyclin A1 Antibody / CCNA1 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length Xenopus laevis Cyclin A1 protein was used as the immunogen for the Cyclin A1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Cyclin A1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Cyclin A1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Cyclin A1

Target: Cyclin A1 (CCNA1)

Alternative Name: Cyclin A1

Background: The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34. The antibody detects Xenopus cyclin A in blots. Cyclin A1 is the embryonic cyclin which is present in Xenopus eggs.

UniProt: P78396

Pathways: Apoptosis, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA