AKR1C1 antibody (full length)

Catalog No. ABIN7878139

The Mouse Monoclonal anti-AKR1C1 antibody (Clone AKR1C1-9318) (ABIN7878139) specifically detects AKR1C1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for AKR1C1 antibody (full length) (ABIN7878139)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AKR1C1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: AKR1C1-9318

Product Details anti-AKR1C1 Antibody

Binding Specificity: full length

Purpose: Dihydrodiol dehydrogenase 1 Antibody / DDH1 / AKR1C1

Purification: Protein G affinity

Immunogen: A recombinant human full-length AKR1C1 protein was used as the immunogen for the Dihydrodiol dehydrogenase 1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Dihydrodiol dehydrogenase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Dihydrodiol dehydrogenase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Alternative Name: Dihydrodiol dehydrogenase 1

Background: DDH1 / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

UniProt: Q04828

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process