DMRT2 antibody (full length)

Catalog No. ABIN7878145

The Mouse Monoclonal anti-DMRT2 antibody (Clone PCRP-DMRT2-1B11) (ABIN7878145) specifically detects DMRT2 in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for DMRT2 antibody (full length) (ABIN7878145)

Target: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DMRT2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: PCRP-DMRT2-1B11

Product Details anti-DMRT2 Antibody

Binding Specificity: full length

Purpose: DMRT2 Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human DMRT2 protein was used as the immunogen for the DMRT2 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the DMRT2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the DMRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DMRT2

Target: DMRT2 (Doublesex and Mab-3 Related Transcription Factor 2 (DMRT2))

Alternative Name: DMRT2

Background: The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

UniProt: Q9Y5R5