ELK1 antibody (full length)

Catalog No. ABIN7878164

This Mouse Monoclonal antibody specifically detects ELK1 in IP. It exhibits reactivity toward Human.

Quick Overview for ELK1 antibody (full length) (ABIN7878164)

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ELK1 antibody is un-conjugated

Application: Immunoprecipitation (IP)

Grade: Carrier-free

Clone: PCRP-ELK1-1B9

Product Details anti-ELK1 Antibody

Binding Specificity: full length

Purpose: ELK1 Antibody / ETS Like-1 protein Elk-1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human ELK1 protein was used as the immunogen for the ELK1 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the ELK1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the ELK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ELK1

Target: ELK1 (ELK1, Member of ETS Oncogene Family (ELK1))

Alternative Name: ELK1

Background: Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1 3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5 element.

UniProt: P19419

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling