EZH2 antibody (full length)

Catalog No. ABIN7878169

The Mouse Monoclonal anti-EZH2 antibody (Clone EZH2-2536) (ABIN7878169) specifically detects EZH2 in WB. The antibody is reactive with Human samples.

Quick Overview for EZH2 antibody (full length) (ABIN7878169)

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EZH2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: EZH2-2536

Product Details anti-EZH2 Antibody

Binding Specificity: full length

Purpose: EZH2 Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human EZH2 protein was used as the immunogen for this EZH2 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the EZH2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the EZH2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for EZH2

Target: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Alternative Name: EZH2

Background: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation