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Ezrin antibody (full length)

The Mouse Monoclonal anti-Ezrin antibody (Clone SPM244) (ABIN7878214) specifically detects Ezrin in WB and IHC (p). The antibody is reactive with Human samples.
Catalog No. ABIN7878214
$317.38
Plus shipping costs $50.00
20 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for Ezrin antibody (full length) (ABIN7878214)

Target

See all Ezrin (EZR) Antibodies
Ezrin (EZR)

Reactivity

  • 165
  • 84
  • 77
  • 9
  • 8
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Human

Host

  • 146
  • 22
  • 1
Mouse

Clonality

  • 124
  • 45
Monoclonal

Conjugate

  • 98
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Ezrin antibody is un-conjugated

Application

  • 140
  • 59
  • 50
  • 20
  • 17
  • 15
  • 13
  • 13
  • 10
  • 9
  • 9
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

SPM244
  • Binding Specificity

    • 30
    • 16
    • 10
    • 10
    • 9
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    Purpose

    Ezrin Antibody / EZR

    Purification

    Protein G affinity chromatography

    Immunogen

    A recombinant human full-length protein was used as the immunogen for this Ezrin antibody.

    Isotype

    IgG2b, kappa
  • Application Notes

    Optimal dilution of the Ezrin antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.2 mg/mL

    Buffer

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store the Ezrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • Target

    Ezrin (EZR)

    Alternative Name

    Ezrin

    Background

    Ezrin, Moesin and Radixin belong to a family of highly homologous Actinassociated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70 % homology with Ezrin and are coexpressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.

    UniProt

    P15311

    Pathways

    Maintenance of Protein Location
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