Fascin antibody (full length)

Catalog No. ABIN7878219

The Mouse Monoclonal anti-Fascin antibody is suitable to detect Fascin in samples from Human. It has been validated for IHC (p).

Quick Overview for Fascin antibody (full length) (ABIN7878219)

Target: Fascin (FSCN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fascin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM133

Product Details anti-Fascin Antibody

Binding Specificity: full length

Purpose: Fascin Antibody

Purification: Protein G affinity chromatography

Immunogen: Full length recombinant human protein was used as the immunogen for the Fascin antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the Fascin antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Fascin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Fascin

Target: Fascin (FSCN1)

Alternative Name: Fascin

Background: Fascin organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. [UniProt]

UniProt: Q16658