Optimal dilution of the Glucose 6-Phosphate Isomerase antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store the Glucose 6-Phosphate Isomerase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
GPI
(Glucose-6-Phosphate Isomerase (GPI))
Alternative Name
Glucose 6-Phosphate Isomerase
Background
In addition to it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency.