Optimal dilution of the Glucose-6-phosphate isomerase antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
-20 °C
Storage Comment
Aliquot the Glucose-6-phosphate isomerase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
GPI
(Glucose-6-Phosphate Isomerase (GPI))
Alternative Name
Glucose-6-phosphate isomerase
Background
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency.