The Mouse Monoclonal anti-GPI antibody (Clone GPI-2439) (ABIN7878295) specifically detects GPI in WB and IHC (p).
The antibody is reactive with Human samples.
Optimal dilution of the Glucose-6-phosphate isomerase antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the Glucose-6-phosphate isomerase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
GPI
(Glucose-6-Phosphate Isomerase (GPI))
Alternative Name
Glucose-6-phosphate isomerase
Background
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Defects in GPI are the cause of hemolytic anemia non-spherocytic due to glucose phosphate isomerase deficiency.