GLG1 antibody (full length)

Catalog No. ABIN7878315

The Mouse Monoclonal anti-GLG1 antibody is suitable to detect GLG1 in samples from Human. It has been validated for IHC (fp) and IHC (fro).

Quick Overview for GLG1 antibody (full length) (ABIN7878315)

Target: GLG1 (Golgi Glycoprotein 1 (GLG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLG1 antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: GLG1-4830

Product Details anti-GLG1 Antibody

Binding Specificity: full length

Purpose: GLG1 Antibody / Golgi Glycoprotein 1

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the GLG1 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the GLG1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the GLG1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GLG1

Target: GLG1 (Golgi Glycoprotein 1 (GLG1))

Alternative Name: GLG1

Background: This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

UniProt: Q92896