Growth Hormone 1 antibody (full length)

Catalog No. ABIN7878325

The Mouse Monoclonal anti-Growth Hormone 1 antibody (Clone GH-3155) (ABIN7878325) specifically detects Growth Hormone 1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Growth Hormone 1 antibody (full length) (ABIN7878325)

Target: Growth Hormone 1 (GH1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GH-3155

Product Details anti-Growth Hormone 1 Antibody

Binding Specificity: full length

Purpose: Growth Hormone Antibody / GH1

Purification: Protein G affinity chromatography

Immunogen: A full-length of human Growth Hormone protein was used as the immunogen for the Growth Hormone antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Growth Hormone antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Growth Hormone antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Growth Hormone

Background: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process