Recombinant Growth Hormone 1 antibody (full length)

Catalog No. ABIN7878327

The Rabbit Monoclonal anti-Growth Hormone 1 antibody is suitable to detect Growth Hormone 1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant Growth Hormone 1 antibody (full length) (ABIN7878327)

Target: Growth Hormone 1 (GH1)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Growth Hormone 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: GH-8215R

Product Details anti-Growth Hormone 1 Antibody

Binding Specificity: full length

Purpose: Growth Hormone Antibody / GH1

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human GH1 protein was used as the immunogen for the Growth Hormone antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Growth Hormone antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Growth Hormone antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Growth Hormone 1

Target: Growth Hormone 1 (GH1)

Alternative Name: Growth Hormone

Background: Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

UniProt: P01241

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process