IRF9 antibody (full length)

Catalog No. ABIN7878453

The Mouse Monoclonal anti-IRF9 antibody is suitable to detect IRF9 in samples from Human. It has been validated for IF and FACS.

Quick Overview for IRF9 antibody (full length) (ABIN7878453)

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IRF9 antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-IRF9-2F8

Product Details anti-IRF9 Antibody

Binding Specificity: full length

Purpose: IRF9 Antibody / Interferon regulatory factor 9

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human IRF9 protein was used as the immunogen for the IRF9 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the IRF9 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IRF9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRF9

Target: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Alternative Name: IRF9

Background: Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

UniProt: Q00978

Pathways: JAK-STAT Signaling, Interferon-gamma Pathway, Hepatitis C