Cytokeratin 13 antibody (full length)

Catalog No. ABIN7878478

The Mouse Monoclonal anti-Cytokeratin 13 antibody (Clone KRT13-2659) (ABIN7878478) specifically detects Cytokeratin 13 in IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for Cytokeratin 13 antibody (full length) (ABIN7878478)

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 13 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: KRT13-2659

Product Details anti-Cytokeratin 13 Antibody

Binding Specificity: full length

Purpose: Cytokeratin 13 Antibody / KRT13 (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human KRT13 protein was used as the immunogen for this Cytokeratin 13 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Cytokeratin 13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Cytokeratin 13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Cytokeratin 13

Target: Cytokeratin 13 (KRT13) (Keratin 13 (KRT13))

Alternative Name: Cytokeratin 13

Background: Cytokeratin 13 (KRT13) is the major acidic keratin, which together with KRT4, its basic partner, is expressed in the suprabasal layers of non-cornified stratified epithelia including tongue mucosa, esophagus, anal canal epithelium, tracheal epithelium, uterine cervix, and urothelium. Defects in the KRT13 gene are a cause of white sponge nevus of cannon (WSN), a rare autosomal dominant disorder, which predominantly affects non-cornified stratified squamous epithelia and is characterized by the presence of soft, white and spongy plaques in the oral mucosa. KRT13 has been used as a marker for non-keratinized squamous epithelium. It is also expressed in various squamous metaplasia, but it is down regulated in squamous dysplasia and squamous carcinoma.

UniProt: P13646