Recombinant Keratin Basic (full length) antibody

Catalog No. ABIN7878521

This Mouse Monoclonal antibody specifically detects Keratin Basic in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Keratin Basic (full length) antibody (ABIN7878521)

Target: Keratin Basic

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RKRTH-8883

Product Details

Binding Specificity: full length

Purpose: Recombinant Basic Cytokeratin Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human KRT76 protein was used as the immunogen for the recombinant Basic Cytokeratin antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Basic Cytokeratin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant Basic Cytokeratin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: Keratin Basic

Alternative Name: Basic Cytokeratin

Background: This mAb recognizes basic (Type II or HMW) cytokeratins, which include 67 kDa (CK1), 64 kDa (CK3), 59 kDa (CK4), 58 kDa (CK5), 56 kDa (CK6), 52 kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 5048, 46, 45, and 40 kDa. mAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52 kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

UniProt: Q01546