MEF2B antibody (full length)

Catalog No. ABIN7878686

This Mouse Monoclonal antibody specifically detects MEF2B in WB, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for MEF2B antibody (full length) (ABIN7878686)

Target: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEF2B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-MEF2B-2F9

Product Details anti-MEF2B Antibody

Binding Specificity: full length

Purpose: MEF2B Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human MEF2B protein was used as the immunogen for the MEF2B antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the MEF2B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MEF2B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MEF2B

Target: MEF2B (Myocyte Enhancer Factor 2B (MEF2B))

Alternative Name: MEF2B

Background: The myocyte enhancer factor-2 (MEF-2) family of transcription factors associate with co-repessors or co-activators to regulate development and function of T cells, neuronal cells, and muscle cells. Four family members, termed MEF-2A, -2B, -2C, and -2D, arise from alternatively spliced transcripts. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including MyoD, myogenin, Myf-5, and MRF4, are one class of identified factors. The MEF-2 family represents a second class of DNA binding regulatory proteins. Each of these proteins binds to the MEF-2 target DNA sequence present in the regulatory regions of many muscle-specific genes.

UniProt: Q02080