NEUROD2 antibody (full length)

Catalog No. ABIN7878708

The Mouse Monoclonal anti-NEUROD2 antibody is suitable to detect NEUROD2 in samples from Human. It has been validated for ELISA, IF and FACS.

Quick Overview for NEUROD2 antibody (full length) (ABIN7878708)

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NEUROD2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-NEUROD2-1G1

Product Details anti-NEUROD2 Antibody

Binding Specificity: full length

Purpose: NEUROD2 Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human NEUROD2 protein was used as the immunogen for the NEUROD2 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the NEUROD2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NEUROD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NEUROD2

Target: NEUROD2 (Neurogenic Differentiation 2 (NEUROD2))

Alternative Name: NEUROD2

Background: Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix(bHLH) transcription factorsthat function as dominant negative regulators and are involved in cell lineage determination and differentiation. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.

UniProt: Q15784