NME1 antibody (full length)

Catalog No. ABIN7878714

The Mouse Monoclonal anti-NME1 antibody is suitable to detect NME1 in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for NME1 antibody (full length) (ABIN7878714)

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NME1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: NME1-2737

Product Details anti-NME1 Antibody

Binding Specificity: full length

Purpose: NME1 Antibody / NM23 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human NME1 protein was used as the immunogen for the NME1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the NME1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the NME1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for NME1

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Alternative Name: NME1

Background: The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor.

UniProt: P15531

Pathways: Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process