PCGF3 antibody (full length)

Catalog No. ABIN7878825

The Mouse Monoclonal anti-PCGF3 antibody is suitable to detect PCGF3 in samples from Human. It has been validated for IF, IHC (p) and FACS.

Quick Overview for PCGF3 antibody (full length) (ABIN7878825)

Target: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PCGF3 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-PCGF3-1D5

Product Details anti-PCGF3 Antibody

Binding Specificity: full length

Purpose: PCGF3 Antibody / Polycomb group RING finger protein 3 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the PCGF3 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the PCGF3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the PCGF3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PCGF3

Target: PCGF3 (Polycomb Group Ring Finger 3 (PCGF3))

Alternative Name: PCGF3

Background: Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. Several members of the PcG contain ring finger domains and are identified as a subclass of RING finger proteins. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteinerich domain that is able to bind two zinc atoms. Proteins that contain the RING-type zinc finger conserved domain are generally involved in the ubiquitination pathway of protein degradation. PCGF3 (polycomb group ring finger 3), also known as RNF3, DONG1 or RNF3A, is a 242 amino acid transcriptional regulator that is encoded by a gene located on human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. PCGF3 exists as two isoforms produced by alternative splicing events.

UniProt: Q3KNV8

Pathways: Chromatin Binding