Recombinant PMEPA1 antibody (full length)

Catalog No. ABIN7878870

The Rabbit Monoclonal anti-PMEPA1 antibody is suitable to detect PMEPA1 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant PMEPA1 antibody (full length) (ABIN7878870)

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PMEPA1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: PMEPA1-6421R

Product Details anti-PMEPA1 Antibody

Binding Specificity: full length

Purpose: Recombinant TMEPAI Antibody / PMEPA1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human PMEPA1/TMEPAI protein was used as the immunogen for the recombinant TMEPAI antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the recombinant TMEPAI antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant TMEPAI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PMEPA1

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Alternative Name: TMEPAI

Background: PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway