Recombinant Osteopontin antibody (full length)

Catalog No. ABIN7878989

This Mouse Monoclonal antibody specifically detects Osteopontin in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Osteopontin antibody (full length) (ABIN7878989)

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteopontin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ROSP-8856

Product Details anti-Osteopontin Antibody

Binding Specificity: full length

Purpose: Uropontin Antibody / SPP1 / Osteopontin

Purification: Protein A/G affinity

Immunogen: Recombinant full-length rat protein was used as the immunogen for the Uropontin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the Uropontin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Uropontin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Osteopontin

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Alternative Name: Uropontin

Background: Osteopontin is a bone matrix protein and a cytokine secreted by activated T cells. Osteopontin (OPN, also designated bone sialoprotein 1, urinary stone protein, spp-1, nephropontin, uropontin) is an extracellular matrix cell adhesion phosphoglycoprotein. OPN is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans, and between collagen fibrils of fully matured hard tissues. While OPN is a major product of osteoblasts, it is also synthesized by brain and kidney cells. OPNs isolated from or secreted by various tissues have molecular weights due to post-translational modifications. OPN functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.

UniProt: P10451

Pathways: Regulation of Cell Size