Recombinant Secretory Component antibody (full length)

Catalog No. ABIN7878997

The Mouse Monoclonal anti-Secretory Component antibody (Clone rSPM217) (ABIN7878997) specifically detects Secretory Component in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Secretory Component antibody (full length) (ABIN7878997)

Target: Secretory Component

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Secretory Component antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RSPM217

Product Details anti-Secretory Component Antibody

Binding Specificity: full length

Purpose: Recombinant Secretory Component Antibody / ECM1

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human protein was used as the immunogen for the recombinant Secretory Component antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Secretory Component antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Secretory Component antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Secretory Component

Target: Secretory Component

Background: This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

UniProt: Q16610